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KMID : 0365819710110020069
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Journal of Pusan Medical College
1971 Volume.11 No. 2 p.69 ~ p.80
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A Study on the Lysozyme Activity of the Human Milk
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Abstract
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The author estimated the lysozyme activity (L. A.) and protein content of 127 specimens of mature
milk and 73 specimens of colostrum or transient milk from healthy Korean women.
They were studied according to the age of month of the infants, number of child-births and the
age of the mothers.
He also estimated the L. A. and protein content from above specimens in order to carry out a comparative study between colostrum and mature milk, colostrum and transient milk, and colostrum and transient milk of primigravida and of multigravida.
The samples were collected from well baby clinic of Pediatric Department of Pusan Medical College Hospital, Pusan Red Cross Hospital, Pusan Sanitary Hospital and other local clinics.
The milk was assayed for lysozyme activity by the method of Litwack, and for protein by the Microkjeldahl method.
The results obtained were as follows;
1) The L. A. of colostrum and transient milk was higher than that of mature human milk.
2) The L.A. of mature human milk was higher during the first 10 to 25 days of the post-partum period(This period was rather short) on the other hand the L. A. was lower from 1 month postpartum and continued at the same level thereafter.
3) The L.A. of mature human milk of multipara was slightly higher than that of primipara. The protein content was found to be the same in both groups.
4). No significant differences were obtained in L. A. or in the protein content of mature human milk in relation to the age of the mothers.
5) The L. A. was higher in colostrum specimens obtained 1 day before delivery to 1 day after delivery than that of transient milk, and the L. A. of early and late transient milk was similar to that of mature human milk.
6) No significant differences were estimated in the L. A. and protein content of colostrum from primigravida and from multigravida.
7) There was no good co-relation between lysozyme activity and protein content of healthy human milk.
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KEYWORD
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